Yes, ideally, he would have become (or realized that he was) strong enough, by season's end, to break up with her --whether he chose to, or not -- which would have brought the relationship out of the "rescue" mode from "Help Me" to a more equal footing, with both parties equally invested and equally capable (and equally stubborn.) But addiction is a process of relapse and recovery rinse and repeat, and relationships between saviors/save-ees rarely end well, so I guess this resolution was more realistic.

And this way, of course, House gets to be right. He predicted all along that it wouldn't last.