I can definitely see House freaking out like this and tearing up his apartment. It was difficult to read, but painfully realistic.

It was really interesting to see both Foreman and Chase talking to him; Chase has a certain, sometimes visible vulnerability. He admires House, cares about his approval, and cares about him. House becoming suicidal would be difficult on him and you really made that come across. I also like how you've kept him completely in character; he would try to stand up to House, tell him the blunt truth, but he would be too soft and hurt by what happened to actually punch him in this case I think. And House, while shaken by what he said, wouldn't want to accept the reality of what he was saying and, as Foreman said, Chase wouldn't have made it come across as well as he could have.

Foreman would have been more casual, more serious about things, but still with glimpses of care underneath.

I could see the wedding photo so clearly in my head; I feel like the description of it and this line:

She could never be happy with you the way you were, and yet you were too terrified of losing her to face up to facts.

sum up House and Cuddy's relationship incredibly well.

I feel like House cares about Cuddy, loves her, but that he looks at their relationship as the answer to all his problems and that ultimately, he will see that it isn't.

I also feel like he is far too terrified to be in a relationship with Wilson, and, like you described in a previous chapter, Wilson seems to be scared as well.

There is one last chapter in this fic and I will be sorry to see it end, but at the same time, am rather curious as to how it does end.